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Updated: Jul 6, 2026

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures
Published on: November 2, 2015
AP-ROP in an infant with minimal oxygen exposure
Mariam J Buksh1, Shuan Dai, Carl A Kuschel
1Newborn Services, National Women's Health, Auckland District Health Board, Auckland, New Zealand. mariamb@adhb.govt.nz
Abstract:
Retinopathy of prematurity (ROP) is a multifactorial disease affecting the developing retinal vasculature and remains an important cause of blindness in very preterm infants. Rush disease, or aggressive posterior ROP (AP-ROP), progresses rapidly to stage 5 disease without exhibiting the classical course that includes stages 1-3. We describe an infant with minimal exposure to oxygen who developed AP-ROP that led to bilateral retinal detachments and a poor visual outcome, despite following current recommended screening guidelines.
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