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Related Experiment Video

Updated: Jul 6, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

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Published on: March 30, 2015

[Changes in renal tumor contrasting in multiphasic SCT].

A V Borisanov, A P Ivanov, V M Buĭlov

    Vestnik Rentgenologii I Radiologii
    |April 3, 2008
    PubMed
    Summary

    Multiphasic spiral computed tomography (SCT) evaluated renal tumor contrast enhancement. The nephrographic phase is most valuable for detecting renal tumors by showing the greatest density gradient.

    Area of Science:

    • Radiology
    • Medical Imaging
    • Oncology

    Background:

    • Renal tumors require accurate diagnostic imaging.
    • Contrast enhancement patterns in computed tomography (CT) can aid in characterizing renal neoplasms.

    Purpose of the Study:

    • To evaluate changes in renal tumor contrast enhancement and parenchyma-tumor density gradients using multiphasic spiral computed tomography (SCT).
    • To determine the optimal CT phase for differentiating renal tumors and hypovascular lesions.

    Main Methods:

    • A hundred and seven patients with renal tumors underwent multiphasic SCT, including native, corticomedullary, nephrographic, and early excretory phases.
    • Renal neoplasms were categorized into intensive, moderate, and low contrast-enhancement groups based on corticomedullary phase enhancement.

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  • Analysis focused on contrast enhancement dynamics and parenchyma-tumor density gradients across different CT phases.

    • Main Results:

    • Intensively and moderately enhancing tumors peaked in the corticomedullary phase, with subsequent density reduction.
    • Lowly enhancing tumors showed gradual enhancement from native to nephrographic phases, with minimal change between nephrographic and excretory phases.
    • The nephrographic phase demonstrated the maximal intact renal parenchyma-tumor density gradient, indicating its high diagnostic value.

    Conclusions:

    • The nephrographic phase of multiphasic SCT is crucial for detecting renal tumors due to the maximal parenchyma-tumor density gradient.
    • Combining native and nephrographic or early excretory phases is useful for differentiating hypovascular renal tumors from cysts.