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Adverse event rates in congenital cardiac catheterization: a new understanding of risks
Lisa Bergersen1, Kimberlee Gauvreau, Kathy J Jenkins
1Children's Hospital Boston, Harvard Medical School-Department of Cardiology, Boston, MA 02115, USA. lisa.bergersen@cardio.chboston.org
Insights
Adverse events (AE) during congenital cardiac catheterization are more common in infants under 1 year old and during interventional procedures. Identifying at-risk populations is crucial for improving patient outcomes.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Congenital heart disease necessitates cardiac catheterization, a procedure with inherent risks.
- Adverse events (AE) can complicate congenital cardiac catheterization, impacting patient safety and outcomes.
- Understanding risk factors for AE is essential for optimizing patient care.
Purpose of the Study:
- To determine the frequency, severity, and causes of AE in congenital cardiac catheterization.
- To identify patient and procedural characteristics linked to AE.
- To enhance risk stratification for adverse outcomes in this patient population.
Main Methods:
- Retrospective analysis of congenital cardiac catheterization procedures.
- Statistical analysis to identify factors associated with AE occurrence and severity.
- Utilizing odds ratios (OR) to quantify risk associated with specific variables.
Main Results:
- Younger age ( < 1 year), interventional procedures, higher procedure risk groups, and hemodynamic vulnerability were significantly associated with increased risk of any AE (all p < 0.001).
- These factors, along with patient weight, also correlated with a higher risk of severe AE, with the exception of young age.
- The study identified key predictors for AE in this specialized patient group.
Conclusions:
- Patient age, procedural type, inherent risk of the procedure, and hemodynamic status are critical factors influencing AE risk.
- Refining risk categorization variables for patient and procedural characteristics can improve the understanding of at-risk populations.
- Enhanced risk assessment can lead to improved safety and outcomes for patients undergoing congenital cardiac catheterization.
Abstract:
We sought to characterize the frequency, severity, and attributability of adverse events (AE) in congenital cardiac catheterization and identify patient and procedural characteristics associated with AE. Risk for any AE was associated with age < 1 year (odds ratio [OR] 2.3), interventional cases (OR 2.2), increasing procedure type risk group (OR 1, 2.0, 2.5), and indicator of hemodynamic vulnerability (OR 1.6), all p < 0.001. Each of these and weight were also associated with increased risk for high severity events, except for young age. Our understanding of populations at risk for adverse outcomes in congenital cardiac catheterization cases can be enhanced through the development and refinement of variables that categorize procedure types and patient characteristics by similar risk for adverse outcomes.
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