Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Placental basal plate with attached myofibers and adverse pregnancy outcomes: A systematic scoping review.

Acta obstetricia et gynecologica Scandinavica·2026

Same author

Use of magnetic resonance imaging as an adjunct to ultrasound for prenatal detection of placenta accreta spectrum.

European journal of obstetrics, gynecology, and reproductive biology·2026

Same author

Prenatal detection of placenta accreta spectrum using a sonographic checklist.

Acta obstetricia et gynecologica Scandinavica·2024

Same author

Spatial proteomics and transcriptomics of the maternal-fetal interface in placenta accreta spectrum.

Translational research : the journal of laboratory and clinical medicine·2024

Same author

Radiomic study of antenatal prediction of severe placenta accreta spectrum from MRI.

The British journal of radiology·2024

Same author

Looking back to look forward: Has the time arrived for active management of obstetricians in placenta accreta spectrum?

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics·2024

Search research articles

Related Experiment Video

Updated: Jan 11, 2026

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

Design and implementation of a high-throughput biological sample processing facility using modern manufacturing

Paul Downey¹, Tim C Peakman

¹UK Biobank, Unit 1 Spectrum Way, Cheadle, Stockport, Cheshire SK3 0SA, UK. paul.downey@ukbiobank.ac.uk

International Journal of Epidemiology

|April 18, 2008

Summary

The UK Biobank study uses modern manufacturing principles to create a high-throughput facility for processing biological samples. This approach ensures a robust resource for future medical research.

More Related Videos

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Published on: December 12, 2019

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics

Published on: September 22, 2011

Related Experiment Videos

Last Updated: Jan 11, 2026

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Published on: December 12, 2019

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics

A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics

Published on: September 22, 2011

Area of Science:

Biomedical research
Biobanking
Manufacturing engineering

Background:

The UK Biobank is a large-scale prospective study collecting health and lifestyle data from 500,000 volunteers.
Data and biological samples are collected over a 4-year period.
The collected data aims to facilitate biological and medical research.

Purpose of the Study:

To establish a high-throughput biological sample processing facility.
To apply modern manufacturing principles in developing the facility.
To ensure the facility supports the long-term goals of the UK Biobank study.

Main Methods:

Utilized modern manufacturing principles to guide facility development.
Implemented automated systems for sample processing.
Established a dedicated process, infrastructure, and staff structure.

Main Results:

A fit-for-purpose facility has been successfully implemented.
The facility integrates technology, systems, and a dedicated process.
An appropriate staff structure is in place to maintain the resource.

Conclusions:

Modern manufacturing principles are suitable for developing high-throughput biological sample processing facilities.
The implemented facility will provide a sustainable resource for the UK Biobank study.
This approach ensures efficient and reliable sample processing for research.