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Updated: Jul 6, 2026

A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
Fibrin sealant for left ventricular rupture after mitral valve replacement
Ovidio A Garcia-Villarreal1, Luis E Casillas-Covarrubias
1Department of Cardiac Surgery, Hospital of Chest and Cardiovascular Disease, Number 34, Mexican Institute of Social Security, Monterrey, Mexico. ovidio@voila.fr
Abstract:
Despite safer surgical procedures, left ventricular rupture remains a rare but potentially lethal complication of mitral valve replacement. The use of fibrin sealant has substantially improved the outcome of many difficult bleeding episodes after cardiac surgery. We describe a case of left ventricular rupture successfully treated with fibrin sealant combined with external Teflon-pledgeted sutures.
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