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Interleukin 18 receptor 1 gene polymorphisms are associated with asthma

Guohua Zhu1, Moira K B Whyte, Jorgen Vestbo

  • 1Genetics, GlaxoSmithKline, Research Triangle Park, NC 27709, USA.

European Journal of Human Genetics : EJHG
|April 3, 2008
PubMed
Summary

Genetic variations in the interleukin 18 receptor (IL18R1) gene are significantly associated with asthma. This study identifies specific IL18R1 polymorphisms linked to asthma, atopic asthma, and bronchial hyper-reactivity, supporting its role in respiratory disease.

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