Related Experiment Video
Updated: Jul 6, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Novel use of a modified Amplatzer Vascular Plug to occlude a patent ductus arteriosus in two patients
Andrew C Glatz1, Christopher J Petit, Matthew J Gillespie
1Division of Cardiology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. glatz@email.chop.edu
Abstract:
We describe two cases in which a patent ductus arteriosus (PDA) was successfully occluded percutaneously, using the novel approach of prefilling an Amplatzer Vascular Plug with embolization coils to decrease the risk of residual shunting through the device. One patient was a small premature neonate, and the other was a child with an aneurismal, tubular PDA with no aortic ampulla. These are situations in which more popular PDA devices such as the Amplatzer Duct Occluder may be contraindicated.

