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Related Experiment Video

Updated: Jul 6, 2026

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods

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Published on: March 10, 2020

Specific weight formula for fetuses with abdominal wall defects.

J Siemer¹, A Hilbert, N Hart

¹Department of Obstetrics and Gynecology, Mannheim University Hospital, Mannheim, Germany. joern.siemer@gyn.ma.uni-heidelberg.de

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology

|April 3, 2008

Summary

A new ultrasound formula accurately estimates fetal weight in fetuses with abdominal wall defects. This specific method offers improved precision compared to existing formulas for conditions like gastroschisis and omphalocele.

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Last Updated: Jul 6, 2026

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Area of Science:

Medical Imaging
Fetal Medicine
Obstetrics

Background:

Accurate fetal weight estimation is crucial for managing pregnancies.
Existing sonographic formulas may lack precision for fetuses with abdominal wall defects.

Purpose of the Study:

To develop and validate a specialized sonographic formula for estimating fetal weight in fetuses diagnosed with abdominal wall defects.

Main Methods:

A stepwise regression analysis was performed on data from 380 preterm singleton pregnancies without anomalies to derive a best-fit weight formula.
The new formula was subsequently evaluated in a cohort of 97 fetuses with gastroschisis or omphalocele.

Main Results:

The novel formula demonstrated a mean percentage error of -0.84 (12.03) and a mean absolute percentage error of 9.29 in the evaluation group.
The developed formula showed significantly higher accuracy in estimating fetal weight compared to commonly used existing formulas.

Conclusions:

The newly developed sonographic weight formula provides an accurate method for estimating fetal weight in fetuses presenting with abdominal wall defects.
This specialized formula enhances prenatal management and clinical decision-making for these specific fetal conditions.