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Wilms tumour in Sudan.

Dafalla O Abuidris1, Mohammed E Elimam, Faisal M Nugud

  • 1Department of Radiation Oncology, Institute of Nuclear Medicine, Molecular Biology and Oncology, University of Gezira, Wad Madani, Sudan. abuidris@yahoo.com

Pediatric Blood & Cancer
|April 4, 2008
PubMed
Summary

Wilms tumour outcomes in Sudan are poor due to delayed presentation and lack of resources. Improving survival requires better awareness, financial support, and specialized pediatric oncology care.

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Area of Science:

  • Pediatric Oncology
  • Cancer Epidemiology
  • Global Health

Background:

  • Wilms tumour is a common childhood cancer with high survival rates in developed countries.
  • Limited data exists on Wilms tumour in Sudan, a region with significant healthcare disparities.

Purpose of the Study:

  • To review the diagnosis and treatment of Wilms tumour in Sudanese children.
  • To identify factors contributing to poor outcomes and propose strategies for improvement.

Main Methods:

  • Retrospective review of patient records at the Institute of Nuclear Medicine, Molecular Biology and Oncology (INMO) from May 1999 to June 2007.
  • Analysis of patient demographics, clinical presentation, disease stage, and treatment completion.

Main Results:

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  • Thirty-seven children with Wilms tumour were identified, with a mean age of 4.1 years.
  • The majority of patients presented with advanced disease (Stage III and IV), and a significant percentage did not receive or complete treatment due to various barriers.
  • Delayed presentation and lack of access to essential resources like finances and transport were major challenges.

Conclusions:

  • Poor Wilms tumour outcomes in Sudan are linked to delayed diagnosis, limited awareness, financial constraints, and inadequate pediatric cancer infrastructure.
  • Recommendations include patient education, neoadjuvant chemotherapy, staff training, and international collaboration to improve survival rates.