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Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
Published on: October 20, 2018
Fabrication, modification, and application of poly(methyl methacrylate) microfluidic chips
Yun Chen1, Luyan Zhang, Gang Chen
1Department of Analytical Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China.
Electrophoresis
|April 4, 2008
Summary
Poly(methyl methacrylate) (PMMA) microfluidic chips offer a low-cost, biocompatible platform. Recent advances focus on fabrication, modification, and applications, paving the way for disposable microfluidic devices.
Area of Science:
- Materials Science
- Microfluidics
- Biotechnology
Background:
- Poly(methyl methacrylate) (PMMA) is a versatile polymer for microfluidic applications.
- PMMA offers advantages such as low cost, optical transparency, and good mechanical properties.
Purpose of the Study:
- To review recent advances in PMMA microfluidic chips.
- To summarize key strategies in fabrication, modification, and application.
- To highlight the potential for disposable microfluidic devices.
Main Methods:
- Literature review of 120 references.
- Analysis of fabrication techniques.
- Evaluation of modification strategies.
- Assessment of diverse applications.
Main Results:
- Significant progress in PMMA microfluidic chip technology over the past decade.
- Identification of key fabrication and modification strategies.
- Demonstration of broad applicability in various fields.
Conclusions:
- PMMA microfluidic chips are suitable for a wide range of applications.
- Advancements facilitate the development of cost-effective, disposable microfluidic devices.
- Future potential for widespread adoption in point-of-care diagnostics and other fields.

