Related Experiment Video
Updated: Jul 6, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Bladder cancer in Native Americans and Alaskan Natives
Richard A Watson1, Monika Sidor
1Department of Surgery, Division of Urology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Hackensack, New Jersey 07601, USA. rwatson@humed.com
Objectives:
The prevalence of bladder cancer among Native Americans/Alaskan Natives (NAs/ANs) is generally considered to be low. However, the relative morbidity and mortality seem high. We have undertaken this survey of the published data to explore and document this observation.
Methods:
An extensive survey of the published data was undertaken. The Surveillance, Epidemiology and End Results data in particular were assessed.
Results:
The incidence of bladder cancer among the NA/AN peoples is inexplicably low. This low incidence is more remarkable, given the widespread use of tobacco products and the disproportionately high incidence of kidney cancer in this same population. Despite this low incidence, NA/AN men and women seem to be at a relatively greater risk of dying of bladder cancer, once it has been diagnosed.
Conclusions:
More and larger studies are needed to clarify and update the incidence, cell type, and clinical outcomes of bladder cancer among NA/AN men and women. Social, economic, and political barriers to treatment also need to be addressed. Effective steps need to be undertaken to ensure more timely diagnosis and treatment of this disease.
Related Concept Videos
Nursing Assessment of the Genitourinary System I: Health History
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Microbiota of the Urogenital Tract

