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Published on: July 20, 2022
Left atrial function and work after surgical ventricular restoration in postmyocardial infarction heart failure
Petros S Dardas1, Antonis A Pitsis, Nikos E Mezilis
1Department of Cardiology and Cardiothoracic Surgery, Thessaloniki Heart Institute, St Luke Hospital, Thessaloniki, Greece.
Insights
Surgical ventricular restoration improved left atrial function in heart failure patients only when left ventricular diastolic function also improved. This highlights the importance of diastolic function for atrial performance post-surgery.
Area of Science:
- Cardiovascular Surgery
- Cardiac Physiology
- Heart Failure Management
Background:
- Extensive anterior myocardial infarction often leads to left ventricular (LV) dilatation and congestive heart failure.
- Surgical ventricular restoration (SVR) is a procedure aimed at improving LV geometry and function in these patients.
- The impact of SVR on left atrial (LA) performance and LV diastolic function requires further investigation.
Purpose of the Study:
- To evaluate the effect of SVR on LA performance and LV diastolic function.
- To identify predictors of improved LA function following SVR in heart failure patients.
Main Methods:
- Prospective study of 17 consecutive patients undergoing SVR and coronary artery bypass grafting.
- Assessment of LA volumes, LA ejection fraction (LAEF), and peak LA kinetic energy (LAKE).
- Evaluation of LV diastolic filling patterns pre- and post-operatively (1-year follow-up).
Main Results:
- LA size and volumes remained unchanged 1 year post-SVR.
- Two groups emerged: one with increased LAEF and LAKE, another with decreased values.
- Significant differences in LV diastolic filling patterns were observed between groups; LA function improved only in patients with better diastolic filling.
Conclusions:
- SVR improves clinical status and LV systolic function in heart failure patients with LV dilatation post-myocardial infarction.
- Improvement in LA function after SVR is contingent upon concurrent improvement in LV diastolic function.
- LV diastolic function is a critical determinant of LA performance following SVR for ischemic cardiomyopathy.
Introduction:
The purpose of the current study was to examine the effect of surgical ventricular restoration in left atrial (LA) performance and left ventricular (LV) diastolic function in patients with congestive heart failure after extensive anterior myocardial infarction.
Methods:
Seventeen consecutive patients (age 63 +/- 9 years, 14 male, 4 with diabetes) were studied prospectively. All patients underwent surgical ventricular restoration and concomitant coronary artery bypass surgery. LA volumes were calculated, as were peak LA kinetic energy (LAKE) and LA ejection fraction (LAEF). LV diastolic filling patterns were also assessed.
Results:
Follow-up period was 1 year. LA size and volumes did not change significantly during the follow-up period. Two distinct groups of patients were identified: group A, in which LAEF and peak LAKE increased, and group B, in which LAEF and peak LAKE decreased. In both groups, the LAEF and peak LAKE appeared to increase or decrease simultaneously and this became evident from the first month after the surgery. However, 1 year after the operation, diastolic filling pattern was significantly different between the two groups. LA function showed improvement only in patients who demonstrated an improvement in indices of diastolic filling pattern.
Conclusions:
Despite improvement in clinical status and indices of LV systolic function in all patients who underwent surgical ventricular restoration for treatment of congestive heart failure as a result of LV dilatation secondary to large myocardial infarction, improvement of LA function occurs in patients with improved LV diastolic function.
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