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Updated: Jul 6, 2026
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The ITS2 Database
Published on: March 12, 2012
SWS: accessing SRS sites contents through Web Services
1Bioinformatics, National Cancer Research Institute (IST), Genova, I-16132, Italy. paolo.romano@istge.it
BMC Bioinformatics
|April 18, 2008
Summary
We developed SRS by Web Services (SWS), a tool enabling programmatic access to biomedical databases via Web Services. This enhances automated in-silico analysis by integrating existing SRS resources into workflow management systems.
Area of Science:
- Bioinformatics
- Computational Biology
- Biomedical Informatics
Background:
- Web Services and Workflow Management Systems automate data analysis in biomedical research.
- Existing biomedical databases often lack programmatic access, limiting integration.
- Sequence Retrieval System (SRS) offers access to many databanks but is not easily accessible via Web Services.
Purpose of the Study:
- To develop a tool enabling programmatic access to information within SRS sites.
- To enhance interoperability between workflow systems and SRS implementations.
- To facilitate automated data retrieval and analysis in biomedical research.
Main Methods:
- Developed 'SRS by WS' (SWS), a suite of Web Services.
- Utilized a database (srsdb) to maintain information on SRS sites.
- Implemented WSDL-compliant clients for accessing SWS.
- Managed access to alternative and up-to-date SRS sites for robustness.
Main Results:
- SWS provides Web Services access to SRS-managed biomedical databanks.
- Results are returned in a text-only format.
- The system supports interoperability with workflow systems.
- SWS enables selection of the most current SRS site.
Conclusions:
- Web Services enabling programmatic access to biomedical databases significantly improve in-silico analysis automation.
- SWS facilitates this by making public SRS databanks programmatically accessible.
- This improves the efficiency and scope of automated bioinformatics workflows.
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