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[Muscle lymphoma: a case report].

S Robaday1, F Héron, N Girszyn

  • 1Département de médecine interne, CHU de Rouen, Rouen cedex, France.

La Revue De Medecine Interne
|April 5, 2008
PubMed
Summary
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Skeletal muscle lymphoma is rare, affecting less than 1.5% of patients. This case highlights pseudotumoral muscle lesions in the lower limbs diagnosed as non-Hodgkin T-cell lymphoma, with MRI aiding diagnosis and biopsy guidance.

Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Lymphoma involvement of skeletal muscle is a rare clinical manifestation, observed in fewer than 1.5% of patients.
  • Non-Hodgkin lymphoma can present with unusual extranodal sites, including muscle tissue, posing diagnostic challenges.

Observation:

  • A 61-year-old male presented with pseudotumoral lesions in the lower limb muscles.
  • Initial presentation mimicked other soft tissue masses, necessitating advanced imaging for characterization.

Findings:

  • Magnetic resonance imaging (MRI) demonstrated characteristic findings of muscle enhancement on T1-weighted post-gadolinium images and high signal intensity on T2-weighted images.
  • These imaging findings were crucial in identifying the extent of muscle infiltration and guiding the biopsy procedure.

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Implications:

  • This case underscores the utility of MRI in diagnosing rare skeletal muscle lymphomas.
  • Accurate diagnosis through imaging and biopsy is essential for appropriate treatment of extranodal lymphoma.
  • Early recognition of pseudotumoral muscle lesions as potential lymphoma can improve patient outcomes.