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Updated: Jul 6, 2026

FISH for Pre-implantation Genetic Diagnosis

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

Genetic screening and counseling.

Mary E Norton¹

¹Perinatal Genetic Services, The Permanente Medical Group, San Francisco, California 94115, USA. mary.e.norton@kp.org

Current Opinion in Obstetrics & Gynecology

|April 5, 2008

Summary

This summary is machine-generated.

Genetic testing advances offer benefits and challenges in prenatal care. New genetic counseling strategies are needed to ensure patients understand all prenatal genetic testing options.

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Area of Science:

Genetics
Prenatal Medicine
Medical Technology

Background:

Genetic technology has rapidly advanced, impacting prenatal screening and diagnostic testing.
Recent changes in recommendations for genetic counseling in prenatal testing are significant.

Purpose of the Study:

To review recent advances in genetic technology for prenatal screening and diagnostic testing.
To examine changes in recommendations for genetic counseling related to prenatal testing.

Main Methods:

Review of current literature and guidelines on prenatal genetic testing.
Analysis of new screening and diagnostic strategies for genetic disorders and chromosomal abnormalities.

Main Results:

Multiple screening tests for single gene disorders, chromosomal abnormalities, and birth defects are now standard for pregnant women.
New approaches include first-trimester screening and sequential testing for chromosomal abnormalities.
Shift away from maternal age-based testing impacts genetic counseling by prenatal care providers.

Conclusions:

Advances in genetic testing provide significant benefits to patients but pose challenges for healthcare providers.
Novel educational and counseling approaches are essential for comprehensive patient review of prenatal genetic testing options.