Operative fetoscopy in complicated monochorionic twins: current status and future direction
Ramen H Chmait1, Rubén A Quintero
1Department of Obstetrics and Gynecology, Keck School of Medicine, University Southern California, Los Angeles, California, USA. Chmait@usc.edu
Current Opinion in Obstetrics & Gynecology
|April 5, 2008
Summary
Prenatal diagnosis and surgical management of complicated monochorionic twins using operative fetoscopy are reviewed. Laser therapy for twin-twin transfusion syndrome and cord occlusion for twin reversed arterial perfusion sequence improve outcomes.
Area of Science:
- Maternal-Fetal Medicine
- Fetal Surgery
- Reproductive Medicine
Background:
- Monochorionic twins face significant risks due to shared placental circulation.
- Complications include twin-twin transfusion syndrome, twin reversed arterial perfusion sequence, and selective intrauterine growth restriction.
- Effective prenatal diagnosis and timely intervention are crucial for improving perinatal outcomes.
Purpose of the Study:
- To review current strategies for prenatal diagnosis of complicated monochorionic twins.
- To emphasize the role of operative fetoscopy in surgical management.
- To discuss recent advancements in fetal interventions for specific complications.
Main Methods:
- Review of current literature on prenatal diagnosis and management of complicated monochorionic twins.
- Emphasis on ultrasound for diagnosis and surveillance.
- Focus on surgical interventions including operative fetoscopy, laser therapy, and umbilical cord occlusion.
Main Results:
- Ultrasound is effective for diagnosing and monitoring various twin complications.
- Operative fetoscopy is a valuable tool for surgical management.
- Laser therapy for twin-twin transfusion syndrome improves perinatal outcomes.
- Umbilical cord occlusion benefits selected cases of twin reversed arterial perfusion sequence.
Conclusions:
- Operative fetoscopy plays a vital role in managing complicated monochorionic twins.
- Fetal interventions, particularly laser therapy and cord occlusion, offer improved outcomes.
- Ongoing research, like trials for selective intrauterine growth restriction, will further refine management strategies.


