Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Spindle Assembly

Spindle Assembly

Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...

Spindle Assembly

Spindle Assembly

Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...

Manufacture of Concrete Masonry Units

Manufacture of Concrete Masonry Units

The process of manufacturing concrete masonry units begins by mixing stiff concrete composed of Portland cement, aggregates, and water. This mixture is then poured into metal molds. To ensure the concrete settles uniformly and to avoid separation of its components, the mixture in the molds is subjected to vibration. Shortly after, the still-wet blocks are removed from the molds and placed on racks.
These wet blocks are then transported for curing, which can occur in one of two environments: a...

Assembly of Complex Microtubule Structures

Assembly of Complex Microtubule Structures

Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.

Oligosaccharide Assembly

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...

Protein Complex Assembly

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types. Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

London Dispersion Governs Stereochemistry, Stability, and Self-Sorting in a System of M<sub>4</sub>L<sub>4</sub> Cages.

Journal of the American Chemical Society·2026

Same author

Chelation-Driven Self-Assembly of Luminescent Magnesium Coordination Cages.

Journal of the American Chemical Society·2026

Same author

Machine Learning Accelerates Crystallization for Structure Determination.

Angewandte Chemie (International ed. in English)·2026

Same author

Steric Hindrance and Secondary Interactions Govern Reconfiguration Between Two Complex Cu<sup>I</sup> Coordination Cages.

Angewandte Chemie (International ed. in English)·2026

Same author

Oppositely-charged coordination cages form a type I porous ionic liquid with two pore sizes.

Materials horizons·2026

Same author

Peptide cages: bioinspired supramolecular architectures for next-generation applications.

Chemical science·2026

Search research articles

Related Experiment Video

Updated: Jul 6, 2026

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

Published on: August 29, 2025

An iminoboronate construction set for subcomponent self-assembly.

Marie Hutin¹, Gérald Bernardinelli, Jonathan R Nitschke

¹Department of Organic Chemistry, University of Geneva, Genève 4, Switzerland.

Chemistry (Weinheim an Der Bergstrasse, Germany)

|April 5, 2008

Summary

This summary is machine-generated.

This study extends subcomponent self-assembly to create complex iminoboronate ester structures. The reversible nature of these bonds allows for predictable substitutions and the formation of intricate molecular architectures.

More Related Videos

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

Related Experiment Videos

Last Updated: Jul 6, 2026

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

Published on: August 29, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

Area of Science:

Supramolecular Chemistry
Organic Synthesis
Materials Science

Background:

Previous work demonstrated copper(I)-templated imine bond formation for complex structure synthesis.
Subcomponent self-assembly offers a modular approach to constructing intricate molecular architectures.
Dynamic covalent chemistry utilizes reversible bond formation for adaptable molecular systems.

Purpose of the Study:

To extend the subcomponent self-assembly concept to iminoboronate ester systems.
To investigate factors influencing iminoboronate ester formation and self-assembly.
To develop rules for predicting and controlling the formation of complex boron-containing structures.

Main Methods:

Reaction of diols, amines, and 2-formylphenylboronic acid to form iminoboronate esters.
Systematic variation of reaction conditions to study factors affecting ester formation.
Analysis of B-O and C=N bond lability for substitution reactions.

Main Results:

Successful generation of iminoboronate esters via reversible B-O and C=N bond formation.
Identification of factors governing the extent of ester formation and self-assembly.
Construction of complex boron-containing structures, including a trigonal cage with six boron centers.
Demonstration of predictable substitution reactions based on electronic properties of subcomponents.

Conclusions:

The subcomponent self-assembly methodology is applicable to the dynamic covalent system of iminoboronate esters.
Predictive rules for self-assembly and substitution reactions were established.
This approach enables the construction of complex, adaptable molecular architectures with multiple boron centers.