Related Experiment Video
Updated: Jul 6, 2026

Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
Published on: April 3, 2026
[Cervical metastatic adenopathy from the oropharynx cancer]
1Clinica ORL, Spitalul Clinic Judeţean de Urgenţă "Sf. Spiridon", Iaşi.
Unlabelled:
Cervical metastatic adenopathy represents quite often the first symptom in many cancers of the upper respiratory and digestive pathways and might be the first symptom in 20-25% of the oropharyngeal cancers.
Material And Method:
The study is based on 243 cases of oropharyngeal cancer admitted to the ENT Clinic, "Sf. Spiridon" Hospital Iaşi within the last ten years.
Results:
By analyzing the evolution of 243 cases of oropharyngeal cancer we conclude: because of the lack of symptoms, the alarming symptom is very often the cervical adenopathy so that the diagnosis is established in the late stages. On the other side, the abundance of the lymphatics of the pharynx make possible the metastatic adenopathy to show in the early stages of evolution of an oropharyngeal cancer.
Conclusion:
Radical neck dissection followed by radiotherapy is proved to be so far, the optimal treatment for cervical metastatic adenopathy.
Related Concept Videos
Cellular Adaptation IV: Dysplasia and Metaplasia
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Pharynx
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer Cell Migration through Invadopodia