Related Experiment Video
Updated: Jul 6, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[Complex brain malformation as a rare cause of neonatal death]
Sibylle Banaschak1, Horst Urbach, Burkhard Madea
1Institut für Rechtsmedizin des Universitätsklinikums Köln.
Abstract:
A dead female neonate was brought to a children's hospital by the mother. The MRI scan suggested a malformation of the brain. Because of the other circumstances of the case (the mother left the hospital unauthorizedly), a forensic autopsy was ordered, in the course of which the brain was removed while the head was totally immersed in water. This method, which was introduced by Prahlow et al., helps to obtain intact brain specimens without interfering with the necessary medicolegal preparations to determine whether the child was born alive. Neuropathological examinations classified the cerebral malformation as (lethal) lissencephaly. Further investigations showed that the mother had lived in Germany without a residence permit.
Related Concept Videos
Neurulation
Brain Abscess l: Introduction
Bacterial Meningitis I: Introduction
Encephalitis l: Introduction
Cerebral Edema ll: Pathophysiology
