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Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Adult Stem Cells

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

Source And Potency Of Stem Cells

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...

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Related Experiment Video

Updated: Jul 6, 2026

Developing HiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays

Developing HiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays

Published on: July 20, 2017

Science and society: a stem cell technology model.

Sorapop Kiatpongsan¹

¹Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama 4 Rd, Pathumwan, Bangkok 10330, Thailand. ksorapop@yahoo.com

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet

|April 9, 2008

Summary

Induced pluripotent stem cells (iPS) offer a revolutionary approach to regenerative medicine, deriving stem cell-like cells from skin cells. This breakthrough advances stem cell research and addresses ethical concerns associated with embryonic stem cells.

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Developing HiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays

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Area of Science:

Biotechnology
Regenerative Medicine
Stem Cell Biology

Background:

Stem cell technology holds transformative potential for treating chronic and degenerative diseases.
Current stem cell research faces bioethical challenges, including embryonic destruction and risks to oocyte donors.
Regenerative medicine is poised to become a major medical field in the next decade.

Purpose of the Study:

To introduce a novel method for generating human embryonic stem cell-like cells.
To explore an alternative to traditional embryonic stem cell derivation.
To address bioethical controversies in stem cell research.

Main Methods:

Derivation of human embryonic stem cell-like cells from human skin cells.
Utilizing induced pluripotent stem cell (iPSC) technology.
Investigating novel methods for stem cell generation.

Main Results:

Successful generation of human embryonic stem cell-like cells from skin cells.
Demonstration of a viable alternative to embryonic stem cell derivation.
Potential to mitigate ethical concerns related to oocyte donation and embryo use.

Conclusions:

Induced pluripotent stem cells (iPSCs) represent a significant advancement in stem cell research.
This innovative approach offers solutions to bioethical issues in stem cell technology.
iPSC technology paves the way for future stem cell-based therapies and regenerative medicine.