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Migraine and Meniere's disease: two different phenomena with frequently observed concomitant occurrences

Titus S Ibekwe1, James A Fasunla, Perpetua U Ibekwe

  • 1ORL Division, Department of Surgery, Irrua Specialist Teaching Hospital and College of Medicine, Ambrose Alli University, Ekpoma, Edo State, Nigeria. ibekwets@yahoo.com

Journal of the National Medical Association
|April 9, 2008
PubMed
Abstract

Insights

Migraine is significantly more common in Meniere's disease patients, suggesting a potential link between these conditions. Further research is needed to understand this association between migraine and Meniere's disease.

Area of Science:

  • Neurology
  • Otolaryngology
  • Epidemiology

Background:

  • Migraine variants can mimic Meniere's disease, raising questions about their relationship.
  • Previous observations suggest a possible association between these two distinct conditions.

Purpose of the Study:

  • To determine the prevalence of migraine in patients diagnosed with Meniere's disease.
  • To investigate a potential linkage between Meniere's disease and migraine within a specific geographical context.

Main Methods:

  • A 10-year retrospective analysis (1996-2005) of patients meeting Meniere's disease criteria.
  • Inclusion of patients with migranous symptoms based on International Headache Society (IHS) criteria.
  • Comparison of migraine prevalence in Meniere's patients with population-based data using statistical tests (Z nonparametric test, P < 0.05).

Main Results:

  • Twenty-five patients (0.22% of 11,463 ENT outpatients) were diagnosed with Meniere's disease.
  • Eight patients (32%) met the IHS criteria for migraine.
  • A statistically significant higher prevalence of migraine was observed in Meniere's patients (32%) compared to the general population (5.3%, P = 0.000).

Conclusions:

  • The elevated prevalence of migraine in Meniere's disease patients indicates a significant association.
  • Further molecular and genetic research is recommended to elucidate the underlying mechanisms of this observed link.

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