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Short sleep duration in infancy and risk of childhood overweight
Elsie M Taveras1, Sheryl L Rifas-Shiman, Emily Oken
1Obesity Prevention Program, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, 133 Brookline Ave, Sixth Floor, Boston, MA 02215, USA. elsie_taveras@hphc.org
Insights
Infants sleeping less than 12 hours daily had higher risks of being overweight by age 3. This study highlights infant sleep duration as a key factor in early childhood obesity prevention.
Area of Science:
- Pediatric Health
- Nutritional Epidemiology
- Sleep Science
Background:
- Childhood obesity is a growing public health concern.
- Early life factors, including sleep, are increasingly recognized as potential contributors to overweight and obesity.
- Understanding the relationship between infant sleep patterns and later weight status is crucial for developing effective interventions.
Purpose of the Study:
- To investigate the association between infant sleep duration and the development of overweight in early childhood.
- To determine if insufficient sleep in infancy predicts higher body mass index (BMI) and increased odds of being overweight at age 3 years.
Main Methods:
- A longitudinal cohort study involving 915 children (Project Viva).
- Mothers reported infant sleep duration at 6 months, 1 year, and 2 years, with a weighted average calculated.
- Multivariate regression analyses were used to assess the impact of sleep duration (<12 hours/day vs. >=12 hours/day) on BMI z-score, skinfold thickness, and overweight status at age 3, adjusting for numerous covariates.
Main Results:
- The average daily sleep duration for infants was 12.3 hours.
- Infants sleeping less than 12 hours per day showed a significantly higher BMI z-score (beta=0.16) and sum of skinfold thicknesses (beta=0.79 mm) at age 3.
- Insufficient infant sleep (<12 hours/day) was associated with doubled odds of being overweight (OR=2.04) by age 3, even after adjusting for multiple confounding factors.
Conclusions:
- Infant sleep duration of less than 12 hours daily is a significant risk factor for developing overweight and increased adiposity in preschool-aged children.
- Promoting adequate sleep in infancy may be a viable strategy for preventing early childhood obesity.
- Further research into the mechanisms linking sleep duration and adiposity is warranted.
Objective:
To examine the extent to which infant sleep duration is associated with overweight at age 3 years.
Design:
Longitudinal survey.
Setting:
Multisite group practice in Massachusetts.
Participants:
Nine hundred fifteen children in Project Viva, a prospective cohort. Main Exposure At children's ages 6 months, 1 year, and 2 years, mothers reported the number of hours their children slept in a 24-hour period, from which we calculated a weighted average of daily sleep.
Main Outcome Measures:
We used multivariate regression analyses to predict the independent effects of sleep duration (< 12 h/d vs > or = 12 h/d) on body mass index (BMI) (calculated as the weight in kilograms divided by the height in meters squared) z score, the sum of subscapular and triceps skinfold thicknesses, and overweight (BMI for age and sex > or = 95th percentile) at age 3 years.
Results:
The children's mean (SD) duration of daily sleep was 12.3 (1.1) hours. At age 3 years, 83 children (9%) were overweight; the mean (SD) BMI z score and sum of subscapular and triceps skinfold thicknesses were 0.44 (1.03) and 16.66 (4.06) mm, respectively. After adjusting for maternal education, income, prepregnancy BMI, marital status, smoking history, and breastfeeding duration and child's race/ethnicity, birth weight, 6-month weight-for-length z score, daily television viewing, and daily participation in active play, we found that infant sleep of less than 12 h/d was associated with a higher BMI z score (beta, 0.16; 95% confidence interval, 0.02-0.29), higher sum of subscapular and triceps skinfold thicknesses (beta, 0.79 mm; 95% confidence interval, 0.18-1.40), and increased odds of overweight (odds ratio, 2.04; 95% confidence interval, 1.07-3.91).
Conclusion:
Daily sleep duration of less than 12 hours during infancy appears to be a risk factor for overweight and adiposity in preschool-aged children.
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