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Updated: Jul 6, 2026

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
Published on: November 17, 2018
Cholesterol-lowering activity of plant sterol-egg yolk lipoprotein complex in rats
Ryosuke Matsuoka1, Ayano Muto, Mamoru Kimura
1R&D Division, Q.P. Corporation, Goka-machi, Sashima-gun, Ibaraki, Japan. ryosuke_matsuoka@kewpie.co.jp
Abstract:
Free plant sterols cannot be dissolved in oil or water. Using free plant sterols and egg yolks, we developed a plant sterol-egg yolk lipoprotein complex (PSY) that can be dispersed in water and considered suitable for use in processed foods. The cholesterol-lowering activity of PSY was equal to that of free plant sterols and plant sterol esters. Consumption of a freeze-dried PSY-containing omelet reduced serum and hepatic cholesterol concentrations. The results suggest that PSY has cholesterol-lowering activity equivalent to that of free plant sterols and plant sterol esters. Moreover, the cholesterol-lowering activity of PSY was maintained in processed foods.
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