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Familial translocation t(1;9) associated with macromastia: molecular cloning of the breakpoints

P Wieacker1, N Apeshiotis, S Jakubiczka

  • 1Institut fur Humangenetik, Otto-von-Guericke-Universitat, Magdeburg, Germany. peter.wieacker@medizin.uni-magdeburg.de

Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
|April 9, 2008
PubMed

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As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...