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Related Experiment Video

Updated: Jul 6, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Cardiac resynchronization therapy: which device to implant?

C Leclercq¹, C Mabo, J C Daubert

¹Département de cardiologie et maladies vasculaires, Centre cardio-pneumologique, CHU Rennes, France. christophe.leclercq@chu-rennes.fr

Archives of Cardiovascular Diseases

|April 9, 2008

Summary

Cardiac resynchronization therapy (CRT) is a proven heart failure treatment. Choosing between pacemakers and ICDs for CRT involves patient factors, benefits, and new devices offering early decompensation detection.

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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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Published on: April 11, 2025

Area of Science:

Cardiology
Medical Devices
Heart Failure Management

Background:

Cardiac resynchronization therapy (CRT) is indicated for moderate to severe heart failure with left ventricular systolic dysfunction and QRS duration > 120 ms.
Heart failure patients face a high risk of sudden cardiac death, often arrhythmic.
Previous ICD trials excluded older patients with more comorbidities, unlike current CRT candidates.

Purpose of the Study:

To discuss device selection (pacemaker vs. ICD) for CRT patients.
To highlight considerations for device choice: benefits, comorbidities, life expectancy, cost-effectiveness, and complications.
To introduce new devices with hemodynamic monitoring for early heart failure decompensation detection.

Main Methods:

Review of existing literature on CRT and ICD therapy in heart failure.
Analysis of patient characteristics relevant to device selection.
Discussion of emerging technologies for hemodynamic monitoring and remote patient management.

Main Results:

Device choice for CRT requires balancing therapeutic benefits against patient-specific factors and potential risks.
Newer devices offer hemodynamic monitoring capabilities for proactive heart failure management.
Home monitoring systems can facilitate early detection of decompensation, potentially reducing hospitalizations.

Conclusions:

Optimizing CRT device selection is crucial for improving outcomes in heart failure patients.
Advanced device technology and remote monitoring enhance the management of heart failure decompensation.
Personalized device selection and proactive monitoring are key to managing complex heart failure populations.