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Updated: Jul 6, 2026
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
Language brain dominance in patients with refractory temporal lobe epilepsy: a comparative study between functional
Denise Ren da Fontoura1, Daniel de Moraes Branco, Mauricio Anés
1Programa de Cirurgia de Epilepsia, Serviço de Neurologia, Hospital São Lucas, Pucrs, Porto Alegre, RS, Brazil. denisefontoura@sapo.pt
Purpose:
To identify brain dominance for language functions with DLT and correlate these results with those obtained from fMRI in patients suffering from intractable temporal lobe epilepsy.
Method:
This study reports on 13 patients who underwent pre-surgical epileptic evaluation between April and October 2004 at the Epilepsy Surgery Program, Hospital Sao Lucas, PUCRS. In DLT, dominance was assessed through a consonant-vowel task, whereas in fMRI patients performed a verb generation task.
Results:
Our results identified a correlation between the fMRI lateralization index and the DLT ear predominance index and reply difference index (r=0.6, p=0.02; Pearson Correlation Coefficient), showing positive correlation between results obtained from fMRI and DLT.
Conclusion:
DLT was found to significantly correlate with fMRI. These findings indicate that DLT (a non-invasive procedure) could be a useful tool to evaluate language brain dominance in pre-surgical epileptic patients as it is cheaper to perform than fMRI.
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