Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Craniovertebral junction database analysis: incidence, classification, presentation, and treatment algorithms.

Arnold H Menezes1

  • 1Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 1824 JPP, Iowa City, IA 52242, USA. arnold-menezes@uiowa.edu

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|April 9, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decompression with or without Duraplasty for Chiari I and Syringomyelia.

The New England journal of medicine·2026
Same author

Calcium pyrophosphate dihydrate crystal deposition (CPPD) in the retro-odontoid tissue with compression of cervicomedullary junction: Analysis of 46 cases (1984-2020) with literature review.

Clinical neurology and neurosurgery·2025
Same author

Unstable C2-3 Posterior Ligamentous Injury in a Pediatric Patient with Successful Nonoperative Treatment: A Case Report.

JBJS case connector·2024
Same author

Database Review of 514 Patients with Os Odontoideum. Detailed Analysis of 258 Surgically Treated (1978-2019).

Advances and technical standards in neurosurgery·2024
Same author

The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium.

Journal of neurosurgery. Pediatrics·2024
Same author

Os odontoideum: database analysis of 260 patients regarding etiology, associated abnormalities, and literature review.

Frontiers in surgery·2023
Same journal

Subacute convexity subdural hematoma in a child with malignant Tourette syndrome: a case report.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

The emerging role of intraoperative nanopore sequencing on the neurosurgical strategy in paediatric embryonal brain tumours.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

The plated bayonet forceps: technical note and illustrative video clips.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

Single-center longitudinal experience with MRgLITT in pediatric neurosurgery: technical evolution, expanding indications, and advanced MRI-driven planning.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

Neuroendoscopic treatment of a rapidly enlarging choroidal fissure cyst: a case report and literature review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

Pediatric intraspinal space-occupying lesions: navigating diagnostic pitfalls, surgical complexity, and neurological outcomes in 27 cases.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
See all related articles

This study reviews 5,300 patients with craniovertebral abnormalities, focusing on 2,000 children. It highlights improved treatment strategies for these complex bony lesions affecting the craniocervical junction.

Area of Science:

  • Neurosurgery
  • Pediatric Neurology
  • Orthopedic Surgery

Background:

  • Traditional posterior decompression for craniocervical junction bony lesions yielded poor results for irreducible ventral compression.
  • Adverse outcomes occurred in 35-40% of patients with fixed anterior abnormalities treated with dorsal decompression.
  • Identifying failure causes and improving treatment necessitated a prospective database analysis.

Purpose of the Study:

  • To analyze a large prospective database of craniovertebral abnormalities, with a focus on pediatric cases.
  • To identify causes of treatment failure and refine management strategies for craniocervical junction pathologies.
  • To develop a comprehensive classification and treatment algorithm for craniovertebral abnormalities.

Main Methods:

Related Experiment Videos

  • Prospective database analysis of 5,300 patients with craniovertebral abnormalities, including 2,000 children.
  • Review of presenting symptoms in pediatric cases, such as failure to thrive, weakness, and neurological deficits.
  • Utilization of advanced imaging techniques and dynamic motion studies; surgical intervention based on reducibility and compression direction.

    • Main Results:

    • Children with craniovertebral abnormalities present with diverse symptoms including failure to thrive, weakness, dysphagia, and sleep apnea.
    • Reducible abnormalities were managed with stabilization, while irreducible ones required immediate decompression and fusion.
    • A treatment algorithm and classification system were developed based on the comprehensive database analysis.

    Conclusions:

    • A refined understanding of craniovertebral abnormalities, particularly in children, has led to improved diagnostic and therapeutic approaches.
    • The developed classification and treatment algorithm provide a framework for managing the full spectrum of craniovertebral pathologies.
    • Prospective data collection is crucial for identifying treatment failures and advancing the management of craniocervical junction disorders.