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Updated: Jul 6, 2026
Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
Published on: May 27, 2022
[Positioning analysis of the Yq11 deletion in a patient with azoospermia]
Xiang-ong Tu1, Feng-ua Lan, Zhong-ong Zhu
1Center for Laboratory Medicine, Fuzhou General Hospital, Nanjing Military Region, Fuzhou, Fujian, 350025 P. R. China. tuxdmed@126.com
Objective:
To locate the deletion region of an azoospermic patient with a large deletion on his Y chromosome long arm.
Methods:
Multiplex polymerase chain reaction was used to amplify fifteen sequence tagged sites (STS), namely sY84, sY86, sY87 in AZFa, sY102, sY117, sY118, sY119, sY115, DYS132, DYS383, sY1015, sY121, sY125, sY127, sY129 and sY134 in AZFb, sY152 in AZFd, sY1258, sY1291, sY254, sY255, sY158 and sY1201 in AZFc, and sY160 in Yq12.
Results:
Only sY84, sY86, sY87, sY102, sY117, sY118, sY119, sY115 and DYS132 could be amplified while the others were negative. The breakpoints were found to locate in an area between AZFb sY115 and DYS383 spanning 8577.
Conclusion:
This study provided the exact breakpoints on Y chromosome AZF region in the patient.
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