Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Cycloaddition Reactions: MO Requirements for Thermal Activation01:16

Cycloaddition Reactions: MO Requirements for Thermal Activation

Thermal cycloadditions are reactions where the source of activation energy needed to initiate the reaction is provided in the form of heat. A typical example of a thermally-allowed cycloaddition is the Diels–Alder reaction, which is a [4 + 2] cycloaddition. In contrast, a [2 + 2] cycloaddition is thermally forbidden.
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction01:22

Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

The radical dimerization of ketones or aldehydes gives vicinal diols through a pinacol coupling reaction. However, the behavior of titanium metals used for the reaction as a source of electrons is unusual. When the reaction is carried out in the presence of titanium, diols can be isolated at low temperatures. Else titanium further reacts with diols, forming alkenes through the McMurry reaction.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ni<sup>II</sup>-Pd<sup>II</sup> as a More Solution-Stable Paddlewheel Alternative to Cu<sup>II</sup>-Cu<sup>II</sup> in Metal-Organic Cages.

Journal of the American Chemical Society·2026
Same author

From statistical mixtures to structural insights: characterisation of heterometallic [M<sub>4</sub>L<sub>6</sub>]<sup>8+</sup> coordination cages using high resolution ion mobility mass spectrometry.

Chemical communications (Cambridge, England)·2026
Same author

Controlling the Arrangement of [Fe<sub>4</sub>L<sub>6</sub>]<sup>8+</sup> Cages in the Solid State.

ChemPlusChem·2026
Same author

Single-Step Synthesis of a Heterometallic [Cu<sub>2</sub>PdL<sub>4</sub>]<sup>2+</sup> Hybrid Metal-Organic Coordination Cage.

Angewandte Chemie (International ed. in English)·2025
Same author

Diastereomer Resolution of M<sub>4</sub> L<sub>6</sub> Coordination Cages by Ultra-High-Resolution Ion-Mobility Mass Spectrometry.

Angewandte Chemie (International ed. in English)·2023
Same author

Synergistic or antagonistic antioxidant combinations - a case study exploring flavonoid-nitroxide hybrids.

Organic & biomolecular chemistry·2023

Related Experiment Video

Updated: Jul 6, 2026

Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

Toward multistation rotaxanes using metalloporphyrin coordination templating.

Kathleen M Mullen1, Maxwell J Gunter

  • 1Department of Chemistry, University of New England, Armidale, NSW, Australia.

The Journal of Organic Chemistry
|April 9, 2008
PubMed
Summary

This study explored templated synthesis of rotaxanes using strapped metalloporphyrins. A click chemistry approach successfully created porphyrinic and crown ether rotaxanes with functionalized threads.

More Related Videos

Synthesis of a Water-soluble Metal&#8211;Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)
08:25

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)

Published on: January 17, 2020

Related Experiment Videos

Last Updated: Jul 6, 2026

Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

Synthesis of a Water-soluble Metal&#8211;Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)
08:25

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks (MOFs)

Published on: January 17, 2020

Area of Science:

  • Supramolecular Chemistry
  • Organic Synthesis
  • Coordination Chemistry

Background:

  • Rotaxanes are mechanically interlocked molecules with potential applications in molecular machines.
  • Metalloporphyrins offer unique electronic and structural properties for supramolecular assemblies.
  • Templated synthesis is crucial for constructing complex molecular architectures like rotaxanes.

Purpose of the Study:

  • To develop efficient methods for the templated synthesis of rotaxanes incorporating strapped metalloporphyrins.
  • To investigate the influence of pyridine moieties as templates and binding sites.
  • To explore the molecular motion of the synthesized rotaxanes in response to external stimuli.

Main Methods:

  • Templated synthesis utilizing pyridine derivatives and strapped metalloporphyrins.
  • Stoppering approach with pyridine esters and rhodium(III) chloride porphyrins.
  • 1,3-dipolar cycloaddition (click reaction) for constructing triazole linkers in rotaxanes.

Main Results:

  • The stoppering approach with pyridine esters and Rh(III)-strapped porphyrins yielded unlinked components.
  • Click chemistry successfully produced porphyrinic (Zn, free base, Rh(III)) and crown ether rotaxanes.
  • Multifunctional threads containing triazole and naphthodiimide units were synthesized.
  • Limited molecular motion was observed in response to acid, solvent, or competing ligands.

Conclusions:

  • The click chemistry approach is more effective for synthesizing rotaxanes with strapped metalloporphyrins compared to the initial stoppering strategy.
  • The flexibility of the strap in some porphyrin systems hindered successful interlocking.
  • Further optimization is needed to achieve controlled molecular motion in these systems.