Related Experiment Video
Updated: Jul 6, 2026

06:51
Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents
Published on: August 10, 2018
siRNAs targeting mouse myostatin
V A Furalyov1, I V Kravchenko, V P Khotchenkov
1Bach Institute of Biochemistry, Russian Academy of Sciences, Leninsky pr. 33, Moscow, Russia.
Biochemistry. Biokhimiia
|April 9, 2008
Abstract:
Eight different mouse myostatin small interfering RNA (siRNAs) were synthesized and tested. Five siRNAs showed a pronounced biological effect reducing myostatin mRNA content. For two of them, the myostatin mRNA level was reduced 3- and 4-fold, respectively. The obtained siRNAs can be used for study of biological effects of myostatin, both in vitro and in vivo.

