Cytogenetic studies in Down syndrome
Related Experiment Videos
I C Verma1, S Mathew, R Elango
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi.
Indian Pediatrics
|September 1, 1991
Abstract:
Cytogenetic studies were carried out in 645 patients with Down syndrome. Free trisomy of chromosome 21 was present in 600 cases (93%). Translocation karyotypes were observed in 26 cases (4%). Seventeen patients (2.6%) had mosaicism. Two (0.3%) patients had additional karyotypic abnormalities along with trisomy 21.