Myocardial infarction on the ICU: can we do better?
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Updated: Jul 6, 2026

Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures
Published on: March 12, 2018
1Department of Cardiology, St Thomas' Hospital, Guys and St Thomas' NHS Foundation Trust, London, SE1 7EH, UK.
Insights
Myocardial infarction frequently occurs in intensive care unit patients, often undetected. Early diagnosis is crucial for targeted therapy and reducing high mortality rates associated with this condition.
Area of Science:
- Cardiology
- Critical Care Medicine
Background:
- Myocardial infarction is a leading cause of death globally.
- Current therapeutic strategies have limitations in reducing mortality.
- Accurate diagnosis in the intensive care unit (ICU) is vital for effective treatment.
Purpose of the Study:
- To evaluate the frequency and clinical presentation of acute myocardial infarction in ICU patients.
- To assess the diagnostic challenges and outcomes of myocardial infarction in the ICU setting.
Main Methods:
- Prospective, non-interventional screening study.
- Inclusion of patients admitted to the intensive care unit.
- Utilized diagnostic approaches for acute myocardial infarction.
Main Results:
- Acute myocardial infarction is frequently observed in ICU patients.
- A significant proportion of myocardial infarctions were clinically silent (not apparent).
- Myocardial infarction in this population is associated with high mortality.
Conclusions:
- Undiagnosed myocardial infarction is common in the ICU.
- Screening approaches can aid in accurate diagnosis.
- Improved diagnosis may lead to better therapeutic strategies and outcomes.
Abstract:
Myocardial infarction remains a major cause of death despite contemporary therapeutic strategies. Diagnosis in the intensive care unit is challenging, but is essential to target therapy accurately. In this issue of Critical Care Lim and colleagues present the results of a prospective non-interventional screening study for acute myocardial infarction in patients admitted to the intensive care unit. Myocardial infarction is observed to occur frequently, often without being clinically apparent, with a high associated mortality. Such approaches may facilitate accurate diagnosis of myocardial infarction in this setting, hence opening the way to improved therapy.
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