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Updated: Jul 6, 2026
06:18
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Dengue virus type 4, Manaus, Brazil
Regina Maria Pinto de Figueiredo1, Felipe Gomes Naveca, Michele de Souza Bastos
1Fundação de Medicina Tropical do Amazonas, Manaus, Brazil. regina68@ig.com.br
Emerging Infectious Diseases
|April 9, 2008
Summary
Dengue virus type 4 (DENV-4) has been detected in Amazonas, Brazil. This finding highlights the presence of DENV-4 and co-infections in the region.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Background:
- Dengue virus (DENV) is a significant global health concern.
- DENV-4 is one of the four serotypes of the dengue virus.
- Surveillance of DENV serotypes is crucial for disease control.
Purpose of the Study:
- To report the detection of dengue virus type 4 (DENV-4) in Amazonas, Brazil.
- To document cases of DENV-4 infection in patients from Manaus.
Main Methods:
- Isolation of virus from patient serum samples.
- Confirmation using serologic and molecular diagnostic tests.
Main Results:
- Dengue virus type 4 (DENV-4) was isolated from three patients in Manaus, Amazonas, Brazil.
- All three cases were confirmed through serological and molecular analyses.
- One patient presented a co-infection with dengue virus type 3 (DENV-3) and DENV-4.
Conclusions:
- DENV-4 is circulating in Amazonas, Brazil.
- The findings underscore the importance of ongoing DENV surveillance in the region.
- Co-infections with different DENV serotypes can occur, potentially complicating clinical management.
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