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Seborrheic inclusion cyst.

E J Brown1, G A Youngberg

  • 1Division of Pathology, Veterans Affairs Medical Center, Johnson City, TN.

Journal of the Tennessee Medical Association
|December 1, 1991
PubMed
Summary
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A rare variant of epidermoid cysts, those with seborrheic keratosis-like linings, can develop after surgical removal of typical seborrheic keratosis. This case highlights an unusual post-excision cyst formation.

Area of Science:

  • Dermatology
  • Pathology
  • Surgical Oncology

Background:

  • Epidermoid cysts are common benign skin tumors.
  • A rare variant, epidermoid cysts with seborrheic keratosis-like linings, has been recently described.
  • The etiology and typical presentation of this variant remain under investigation.

Observation:

  • A patient presented with a cyst exhibiting features of both epidermoid cyst and seborrheic keratosis.
  • This specific cyst developed subsequent to the complete excision of a pre-existing, histologically confirmed seborrheic keratosis.
  • The cyst lining mimicked features typically seen in seborrheic keratosis, presenting a diagnostic challenge.

Findings:

  • Histopathological examination confirmed the presence of an epidermoid cyst with atypical lining cells resembling those of a seborrheic keratosis.

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  • The findings suggest a potential link between prior seborrheic keratosis excision and the development of this rare cyst variant.
  • This represents a novel observation of post-surgical cyst formation with specific histological characteristics.

    • Implications:

    • This case expands the understanding of epidermoid cyst variants and their potential development pathways.
    • It suggests that surgical trauma or altered tissue environment following seborrheic keratosis excision may predispose to the formation of these unique cysts.
    • Further research is warranted to elucidate the precise mechanisms and clinical significance of epidermoid cysts with seborrheic keratosis-like linings.