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Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
Published on: July 14, 2015
Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography
Hua Zhong1, Guiru Zhu, Peiyuan Wang
1State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.
Abstract:
The silica-based monolith exhibiting a hierarchical bimodal porous structure has been directly synthesized via lytropic mesophase. The hydrolysis and condensation of tetramethoxysilane (TMOS) in the presence of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (P123) and acetic acid results in silica monolith with MSU-type mesoporous structure embedded in the skeleton of the interconnected macropore. The silica monolith with bimodal porous structure can separate benzene and phenol with high flow rate and low back-pressure. Moreover, the chromatographic property of C18-grafted silica monolith is investigated in the separation of aromatic molecules. Our primary result shows that the silica monolith with interconnected macropore and MSU-type mesopore is a promising packing material as stationary phase for high performance liquid chromatography.
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