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Long-term Depression01:05

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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
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Depression in elderly life sentence prisoners.

Nicholas Murdoch1, Paul Morris, Clive Holmes

  • 1Memory Assessment and Research Centre, University of Southampton, Southampton, UK. kitnocks@zoom.co.uk

International Journal of Geriatric Psychiatry
|April 9, 2008
PubMed
Summary

Depression is common in older prisoners serving life sentences. Chronic physical ill health, not imprisonment itself, is the primary risk factor for depression in this vulnerable population.

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Area of Science:

  • Geriatric Psychiatry
  • Criminology
  • Public Health

Background:

  • The aging prison population, particularly those serving life sentences, presents a growing concern.
  • Limited understanding exists regarding the prevalence and causes of depression among elderly prisoners.

Purpose of the Study:

  • To investigate the prevalence of depression in elderly prisoners serving life sentences.
  • To identify risk factors associated with depression in this demographic.

Main Methods:

  • A study involving 121 elderly prisoners with life/indeterminate sentences in UK prisons.
  • Utilized the Geriatric Depression Scale to assess depression.
  • Analyzed the correlation between depression scores and prison-specific/non-specific variables.

Main Results:

  • Over 50% of participants scored above the threshold for mild depression.
  • No significant association found between depression scores and sentence length or other prison-related factors.
  • A strong correlation was identified between depression scores and pre-existing chronic physical ill health.

Conclusions:

  • Depression is highly prevalent among elderly prisoners serving long sentences.
  • The primary driver of depression in this population appears to be chronic physical ill health, rather than the effects of incarceration itself.