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Updated: Jul 6, 2026
04:56
Modified Octopus Technique for Thoracoabdominal Aortic Aneurysm
Published on: August 1, 2025
Thoracic aortic aneurysm syndrome in children
Giorgio Zanotti1, Luca Vricella, Duke Cameron
1Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Summary
Pediatric thoracic aortic aneurysms often stem from connective tissue disorders like Marfan syndrome. Identifying these syndromes is key to managing and treating aortic aneurysms in children.
Area of Science:
- Cardiology
- Genetics
- Pediatric Surgery
Background:
- Thoracic aortic aneurysms (TAAs) in children differ significantly from adults, frequently linked to underlying genetic connective tissue disorders.
- Recognizing specific phenotypic clues aids in identifying pediatric patients at elevated risk for TAAs.
Purpose of the Study:
- To review the common connective tissue disorders associated with pediatric TAAs.
- To discuss the diagnostic and surgical management strategies tailored to specific pediatric TAA etiologies.
Main Methods:
- Literature review focusing on pediatric thoracic aortic aneurysms and associated connective tissue syndromes.
- Analysis of diagnostic criteria and surgical indications for Marfan syndrome, Loeys-Dietz syndrome, and bicuspid aortic valve syndrome in pediatric populations.
Main Results:
- Marfan syndrome, Loeys-Dietz syndrome, and bicuspid aortic valve syndrome are the predominant causes of TAAs in children.
- Surgical indications and procedural options vary based on the underlying diagnosis and patient-specific factors.
Conclusions:
- Early identification of connective tissue disorders is crucial for proactive management of pediatric TAAs.
- Tailored surgical approaches based on specific genetic syndromes improve outcomes for children with thoracic aortic aneurysms.
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