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Updated: Jul 6, 2026
Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
Published on: May 12, 2011
[Removal and plastic reconstructive surgery of orbital neurofibroma]
Xian-Qun Fan1, Ming Lin, Jin Li
1Department of Ophthalmology, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200011, China.
Objective:
To investigate the safety and efficacy of surgical management of orbital neurofibroma (NF).
Methods:
Twenty-six patients with orbitotemporal NF underwent tumor resection. And then 12 of the 26 patients that were of Jackson group I, underwent blepharoplasty surgery, including lid plastic and reconstructive surgery, lateral canthal reattachment and ptosis surgery. Ten patients of group II underwent blepharoplasty combined with orbital reconstruction. And 4 patients of group III underwent blepharoplasty surgery, orbital reconstruction, and hydroxyapatite orbital implanting. The functionally useless eyes of 2 patients were retained for cosmetic appearance.
Results:
There was no recrudescence after neurofibroma resection. 10 patients had their vision acuity improved. All patients obtained satisfying results after eyelid and orbital plastic surgery. 2 patients relapsed into ptosis that was cured with further frontalis suspension procedure with autogenous fascia lata.
Conclusion:
Neurofibroma removal surgery is a safe and effective treatment method for NF patients. The periorbital appearance and visual acuity of patients with orbitotemporal NF can be significantly improved through oculoplastic surgery.
