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Fetal growth retardation and structural anomalies
J M van Vugt1, V H Karsdorp, R M van Zalen-Sprock
1Department of Obstetrics and Gynecology, Free University Hospital, Amsterdam, The Netherlands.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
|December 1, 1991
Summary
Intra-uterine growth retardation (IUGR) is linked to congenital malformations in 21.8% of cases. Early ultrasound screening for all pregnant women can help detect these issues and reduce perinatal mortality.
Area of Science:
- Perinatology
- Medical Genetics
- Obstetrics
Background:
- Intra-uterine growth retardation (IUGR) is a significant contributor to perinatal mortality.
- Maternal factors influence fetal growth, and IUGR is associated with congenital anomalies.
Purpose of the Study:
- To evaluate the association between Intra-uterine growth retardation (IUGR) and congenital malformations.
- To determine the prevalence of congenital anomalies in fetuses diagnosed with IUGR.
Main Methods:
- A 10-year retrospective study of all collected IUGR cases.
- Level 3 ultrasound examinations were utilized for anomaly detection.
Main Results:
- Congenital malformations were identified in 21.8% of fetuses with IUGR.
- Common anomalies included chromosomal abnormalities, and renal and central nervous system disorders.
Conclusions:
- A strong association exists between IUGR and congenital malformations.
- Recommend routine ultrasound screening at 16-18 weeks for all pregnant women to optimize delivery and reduce perinatal deaths.