Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

Diabetic Foot Ulcer

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...

Arteries of Lower Limbs

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Peripheral Artery Disease IV: Nursing Management

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patient reported outcomes following surgical reconstruction of acquired Charcot foot deformity.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons·2026

Same author

Diabetic Deformities of the Lesser Toes.

Clinics in podiatric medicine and surgery·2026

Same author

Cutaneous Laser Therapy for Residual Limb Skin Pathology: A Narrative Review Bridging Dermatologic Laser Research With Clinical Perspectives and Considerations for Multidisciplinary Care Teams.

Cureus·2026

Same author

Correction: Integrating Gait Analysis Systems in Clinical Rehabilitation Settings for Individuals With Lower Limb Amputation: A Narrative Review.

Cureus·2025

Same author

Integrating Gait Analysis Systems in Clinical Rehabilitation Settings for Individuals With Lower Limb Amputation: A Narrative Review.

Cureus·2025

Same author

Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.

Advances in wound care·2025

Search research articles

Related Experiment Videos

Controversies in lower extremity amputation.

Michael S Pinzur¹, Frank Gottschalk, Marco Antonio Guedes de Souza Pinto

¹Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, Illinois, USA.

Instructional Course Lectures

|April 11, 2008

Summary

Amputation surgery is reconstructive, initiating rehabilitation. It is often superior to limb salvage, requiring careful planning for optimal functional outcomes in amputee patients.

Related Experiment Videos

Area of Science:

Orthopedic Surgery
Rehabilitation Medicine
Prosthetics

Background:

Lessons from World War II veterans with amputations inform current practices.
Amputation surgery is viewed as a critical first step in patient rehabilitation.

Purpose of the Study:

To emphasize amputation as reconstructive surgery.
To highlight amputation as a viable alternative to limb salvage.
To outline key considerations for successful amputation and rehabilitation.

Main Methods:

Review of historical experiences and surgical principles.
Analysis of decision-making factors in amputation level selection.
Evaluation of prosthetic considerations for residual limb function.

Main Results:

Amputation is frequently a more appropriate choice than limb salvage.
Successful outcomes depend on realistic functional expectations and patient-specific needs.
Amputation can range from life-saving to enabling a return to an active life.

Conclusions:

Amputation surgery is fundamentally reconstructive.
Optimal patient outcomes necessitate a thorough understanding of residual limb anatomy and prosthetic integration.
Careful goal setting and patient-centered decision-making are crucial for amputation success.