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Bulged adenosine influence on the RNA duplex conformation in solution.

Lukasz Popenda1, Ryszard W Adamiak, Zofia Gdaniec

  • 1Institute of Bioorganic Chemistry, Polish Academy of Science, Noskowskiego 12/14, 61-704 Poznań, Poland.

Biochemistry
|April 11, 2008
PubMed
Summary

This study reveals how an adenine bulge in RNA duplexes causes structural distortions. The bulged adenine stacks within the helix, influencing overall RNA structure and helical parameters.

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