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Related Concept Videos

Somatosensation01:33

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
Sympathetic Activation01:16

Sympathetic Activation

The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
Stereotype Threat and Self-fulfilling Prophecies02:09

Stereotype Threat and Self-fulfilling Prophecies

When we hold a stereotype about a person, we have expectations that he or she will fulfill that stereotype. A self-fulfilling prophecy is an expectation held by a person that alters his or her behavior in a way that tends to make it true. When we hold stereotypes about a person, we tend to treat the person according to our expectations. This treatment can influence the person to act according to our stereotypic expectations, thus confirming our stereotypic beliefs. Research by Rosenthal and...

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Observing the Transformation of Bodily Self-consciousness in the Squeeze-machine Experiment
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Somatization and stimulus entrapment.

Russell Meares1, Friederike Gerull, Anthony Korner

  • 1Westmead Hospital and Brain Dynamics Centre, University of Sydney, Sydney, NSW, Australia. rmeares@med.usyd.edu.au

The Journal of the American Academy of Psychoanalysis and Dynamic Psychiatry
|April 11, 2008
PubMed
Summary
This summary is machine-generated.

A "vicious circle" hypothesis explains somatization disorder, involving impaired pain inhibition and attention-driven amplification. Therapy focusing on inner material may help overcome this cycle.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Psychology

Background:

  • Somatization disorder, as defined by the DSM, is a common clinical presentation.
  • A
  • vicious circle
  • hypothesis is proposed to explain its underlying mechanisms.
  • This model integrates neurobiological and psychological factors.

Purpose of the Study:

  • To present a
  • vicious circle
  • hypothesis for somatization disorder.
  • To explore the roles of impaired inhibitory systems and attentional amplification.
  • To examine data from borderline patients as a model.

Main Methods:

  • Review of existing literature and clinical data.
  • Focus on the
  • medial pain system
  • and its inhibitory functions.
  • Analysis of event-related potentials (P3a components) to assess prefrontal inhibitory function.

Main Results:

  • Somatization involves a failure of higher-order inhibitory systems in the
  • medial pain system
  • .
  • Attention amplifies stimulus intensity, exacerbated by attentional and sensory modulation failures.
  • Enlarged P3a components in borderline patients suggest diminished prefrontal inhibitory function.

Conclusions:

  • The
  • vicious circle
  • hypothesis provides a framework for understanding somatization.
  • Impaired inhibitory control within the
  • medial pain system
  • contributes to pain prominence.
  • Therapy targeting
  • inner
  • material may alleviate
  • stimulus entrapment
  • in somatization.