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Fresh frozen plasma transfusion for reversal of prolonged post-anaesthesia apnoea
A J van Gammeren1, C M Cobbaert, C J M Schrauwen
1Department of Clinical Chemistry and Haematology, Amphia Hospital, The Netherlands. avangammeren@amphia.nl
Transfusion Medicine (Oxford, England)
|April 11, 2008
Abstract:
An 18-year old woman admitted for tonsillectomy developed prolonged post-operative paralysis after anaesthesia with mivacurium. Investigation revealed a decreased cholinesterase activity because of a homozygous atypical and heterozygous K variant of the cholinesterase gene. Transfusion of fresh frozen plasma was associated with reversal of the respiratory paralysis and complete recovery.

