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Updated: Mar 24, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Economic evaluation of screening for open-angle glaucoma.

Rodolfo A Hernández1, Jennifer M Burr, Luke D Vale

  • 1University of Aberdeen, Aberdeen, Scotland, UK. r.a.hernandez@abdn.ac.uk

International Journal of Technology Assessment in Health Care
|April 11, 2008
PubMed
Summary

Population screening for open-angle glaucoma (OAG) is generally not cost-effective in the UK. However, targeted screening for specific high-risk subgroups may offer better value.

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Area of Science:

  • Ophthalmology
  • Health Economics
  • Public Health

Background:

  • Open-angle glaucoma (OAG) is a leading global cause of blindness.
  • Assessing the economic viability of OAG screening is crucial for healthcare resource allocation.

Purpose of the Study:

  • To evaluate the cost-effectiveness of different open-angle glaucoma screening strategies in the United Kingdom.
  • To compare screening versus opportunistic case finding for OAG.

Main Methods:

  • A Markov model was utilized to estimate lifetime costs and benefits.
  • Strategies included assessments by glaucoma-trained optometrists (GO) or technicians.
  • Data were sourced from systematic reviews, with sensitivity analyses performed.

Main Results:

  • Screening cost-effectiveness increased with higher prevalence and longer re-screening intervals (10 years).
  • Technician-led screening was more cost-effective than GO-led screening.
  • Screening was unlikely to be cost-effective at low prevalence levels (<1%) or for GO strategy at any level.

Conclusions:

  • Widespread population screening for OAG in the UK is unlikely to be cost-effective.
  • Targeted screening approaches for specific high-risk subgroups may be justifiable.