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Related Concept Videos

Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
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Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
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Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...
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Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
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Related Experiment Video

Updated: Jul 6, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

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Probable occupational endophthalmitis from Bacillus cereus.

Maria F Martinez1, Ted Haines, Marge Waller

  • 1London District Worker's Health Clinic, London, Ontario, Canada.

Archives of Environmental & Occupational Health
|April 11, 2008
PubMed
Summary

Endophthalmitis, a severe eye infection, can occur after injury or surgery. This case highlights a potential risk from occupational exposure to metalworking fluid aerosols in machine operators.

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Last Updated: Jul 6, 2026

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Area of Science:

  • Ophthalmology
  • Occupational Health

Background:

  • Endophthalmitis is a serious intraocular infection.
  • Causes include penetrating trauma, ocular surgery, and hematogenous spread.
  • Prompt diagnosis and treatment are crucial to prevent vision loss.

Observation:

  • A 44-year-old male machine operator was evaluated.
  • The patient had significant occupational exposure to metalworking fluid aerosols.
  • Exposure originated from a high-speed grinder producing fine particles.

Findings:

  • The patient presented with symptoms suggestive of endophthalmitis.
  • A potential link between metalworking fluid aerosol exposure and endophthalmitis is investigated.
  • Microbial contamination of aerosols may be a contributing factor.

Implications:

  • Occupational safety measures may need re-evaluation for workers exposed to metalworking fluids.
  • Further research is warranted to confirm the causal relationship.
  • This case underscores the importance of considering environmental exposures in infectious disease etiology.