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A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
A single center's experience with the Ross procedure in pediatrics
Edward Kirkpatrick1, Roger Hurwitz, John Brown
1Pediatric Cardiology, Riley Hospital for Children, 702 Barnhill Dr., Indianapolis, IN 46202, USA. Ekirkpatrick@chw.org
Pediatric Cardiology
|April 11, 2008
Summary
The Ross procedure for aortic valve replacement in children shows good survival rates but requires reoperation over time. This study highlights its effectiveness and potential need for future interventions in pediatric patients.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Thoracic Surgery
Background:
- Pulmonary autograft use for aortic valve replacement (AVR) is increasing in pediatric patients.
- The Ross procedure is a common AVR technique in children.
Purpose of the Study:
- To evaluate the outcomes of the Ross procedure in pediatric patients.
- To assess survival, reoperation rates, and echocardiographic findings after Ross procedure.
Main Methods:
- Retrospective review of pediatric patients (<18 years) who underwent the Ross procedure between 1993 and 2005.
- Analysis of clinical and echocardiographic data.
- Statistical analysis of survival and reoperation-free rates.
Main Results:
- Mortality rate was 3.3%.
- 10-year overall survival was 96.7%.
- 10-year freedom from reoperation (autograft or homograft) was 66.2%, and from left ventricular outflow tract reoperation was 60.5%.
- 76% of patients had mild or less aortic regurgitation at follow-up.
- 52% experienced dilation of the sinuses of Valsalva.
Conclusions:
- The Ross procedure offers good intermediate survival and growth potential for eligible pediatric patients.
- A time-dependent need for reoperation exists, necessitating long-term monitoring.
- This AVR option demonstrates favorable outcomes compared to alternatives in the pediatric population.
