Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioreactor Design and Operational System01:29

Bioreactor Design and Operational System

Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
Bioreactor Controls-II01:18

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...
Typical Model Studies01:30

Typical Model Studies

Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
The Winogradsky Column01:27

The Winogradsky Column

A Winogradsky column provides a powerful tool for studying microbial ecology and metabolic interactions in a stratified, self-contained environment. This artificial ecosystem, developed by Sergei Winogradsky in the late 19th century, replicates the complex biogeochemical gradients found in natural sediments, allowing researchers to observe microbial succession and interactions over time.The column is typically assembled in a transparent glass cylinder filled halfway with sediment mixed with...
Designing Growth Media for Bioreactors01:30

Designing Growth Media for Bioreactors

Growth media provide essential nutrients that support cell growth and metabolism, thereby enhancing the yield of valuable products such as enzymes, antibiotics, and biomass. Designing an effective growth medium involves balancing all components to prevent nutrient limitations or toxic excesses, both of which can impair growth and reduce product yields.Composition of a Typical Growth MediumA typical growth medium contains carbon and nitrogen sources, salts, vitamins, trace elements, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Community assembly following disturbance in batch anaerobic digesters displays highly reproducible secondary succession and a shifting stochastic-deterministic balance.

Frontiers in microbiomes·2026
Same author

The progressive shift in anaerobic digestion communities under extreme propionate levels led to a redundant microbiome capable of producing methane.

Journal of environmental management·2025
Same author

Effect of the Extraction Temperature on the Physicochemical, Functional and In Vitro Protein Digestibility of Cherimoya (Annona cherimola Mill.) Seed Composite.

Plant foods for human nutrition (Dordrecht, Netherlands)·2025
Same author

Structural, magnetic, and luminescent properties of NaGdF<sub>4</sub>:Nd<sup>3+</sup>@Fe<sub>3</sub>O<sub>4</sub>nanocomposites.

Nanotechnology·2024
Same author

Plant-Based Fermented Beverages: Nutritional Composition, Sensory Properties, and Health Benefits.

Foods (Basel, Switzerland)·2024
Same author

Impact of the droplet size of canola oil-in-water emulsions on the rheology and sensory acceptability of reduced-milk fat stirred yogurt.

Journal of food science and technology·2022

Related Experiment Video

Updated: Jul 6, 2026

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities
08:13

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities

Published on: December 25, 2015

Hydrodynamic characterization of a column-type prototype bioreactor.

Teodoro Espinosa-Solares1, Marcos Morales-Contreras, Fabián Robles-Martínez

  • 1Departamento de Ingeniería Agroindustrial, Universidad Autónoma Chapingo, Chapingo, Estado de México, México. espinosa@correo.chapingo.mx

Applied Biochemistry and Biotechnology
|April 11, 2008
PubMed
Summary

This study introduces a novel bioreactor for treating agro-food wastewater using pneumatic agitation. Non-Newtonian fluid properties were found to increase mixing and circulation times in the novel bioreactor design.

More Related Videos

Power Input Measurements in Stirred Bioreactors at Laboratory Scale
10:49

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Published on: May 16, 2018

Experimental Column Setup for Studying Anaerobic Biogeochemical Interactions Between Iron (Oxy)Hydroxides, Trace Elements, and Bacteria
06:52

Experimental Column Setup for Studying Anaerobic Biogeochemical Interactions Between Iron (Oxy)Hydroxides, Trace Elements, and Bacteria

Published on: December 19, 2017

Related Experiment Videos

Last Updated: Jul 6, 2026

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities
08:13

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities

Published on: December 25, 2015

Power Input Measurements in Stirred Bioreactors at Laboratory Scale
10:49

Power Input Measurements in Stirred Bioreactors at Laboratory Scale

Published on: May 16, 2018

Experimental Column Setup for Studying Anaerobic Biogeochemical Interactions Between Iron (Oxy)Hydroxides, Trace Elements, and Bacteria
06:52

Experimental Column Setup for Studying Anaerobic Biogeochemical Interactions Between Iron (Oxy)Hydroxides, Trace Elements, and Bacteria

Published on: December 19, 2017

Area of Science:

  • * Biochemical Engineering
  • * Environmental Engineering
  • * Waste Management

Background:

  • * Agro-food industries generate substantial organic residues requiring effective treatment.
  • * Anaerobic digestion in bioreactors is a viable solution for processing these residues.
  • * Optimizing bioreactor design is crucial for efficient wastewater treatment.

Purpose of the Study:

  • * To design and evaluate a novel 18-L bioreactor for wastewater treatment.
  • * To investigate the impact of pneumatic agitation and semispherical baffles on fluid dynamics.
  • * To analyze the effects of Newtonian and non-Newtonian fluid properties on mixing and circulation.

Main Methods:

  • * Development of a novel 18-L bioreactor featuring pneumatic agitation and semispherical baffles.
  • * Flow pattern visualization using particle tracer technique.
  • * Measurement of circulation and mixing times using particle tracer and thermal techniques.
  • * Simulation of operational conditions using Newtonian and non-Newtonian fluids.

Main Results:

  • * Non-Newtonian fluid properties were observed to reduce mixed zones within the bioreactor.
  • * Increased circulation and mixing times were recorded with non-Newtonian fluids compared to Newtonian fluids.
  • * Circulation time measurements were consistent between thermal and particle tracer methods.
  • * Dimensionless mixing time was successfully predicted using an equivalent Froude number.

Conclusions:

  • * The novel bioreactor design demonstrates potential for effective wastewater treatment.
  • * Fluid rheology significantly influences mixing efficiency and hydrodynamics in the bioreactor.
  • * The developed predictive model for mixing time offers valuable insights for bioreactor optimization.