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[Gastric fibroid polyp in a 4-month-old girl with Costello syndrome]

R Campus1, M Di Rocco, A R Sementa

  • 1Pronto Soccorso Chirurgico, Istituto Giannina Gaslini, Genova. rixcampus@hotmail.com

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|April 12, 2008
PubMed

Insights

A rare gastric fibroid polyp was found in an infant with Costello syndrome. This genetic disorder has a high tumor frequency, and this case marks the first documented instance of this specific tumor type.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Genetics
  • Surgical Oncology

Background:

  • Costello syndrome is a rare genetic disorder associated with a high predisposition to developing various tumors.
  • Gastric fibroid polyps are uncommon benign neoplasms of the stomach.

Observation:

  • A 4-month-old female infant presented with an incidentally discovered gastric fibroid polyp.
  • Diagnostic imaging, including sonography and computerized tomography, confirmed the presence of the gastric lesion.
  • The infant exhibited clinical features consistent with Costello syndrome.

Findings:

  • The gastric fibroid polyp, a rare benign tumor, was successfully surgically excised.
  • This case represents the first documented instance of a gastric fibroid polyp occurring in an individual with Costello syndrome.

Implications:

  • This finding expands the spectrum of gastrointestinal manifestations associated with Costello syndrome.
  • Highlights the importance of vigilant surveillance for neoplasms in patients with Costello syndrome.
  • Contributes to understanding the tumorigenesis in rare genetic syndromes.

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