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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[How to investigate sleep related breathing disorders in children?]
I Rochat1, S Guinand, C Barazzone
1Départment de l'enfant et de l'adolescent, Hôpital des enfants, Genève.
Insights
Early identification and treatment of pediatric sleep-related breathing disorders (SRBD) are crucial for preventing neurocognitive deficits. Persistent nighttime snoring is a key indicator, with polysomnography and oximetry aiding diagnosis.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Neurodevelopmental Pediatrics
Background:
- Sleep-related breathing disorders (SRBD) significantly impair children's neurocognitive development.
- Unlike adults, children with SRBD often exhibit behavioral issues and learning disabilities rather than overt sleepiness.
- Sustained nighttime snoring serves as a valuable initial screening tool for SRBD in pediatric populations.
Purpose of the Study:
- To highlight the critical need for early detection and management of pediatric SRBD.
- To discuss diagnostic approaches for SRBD in children.
- To emphasize the implications of SRBD on neurocognitive outcomes.
Main Methods:
- Review of current diagnostic standards for pediatric SRBD.
- Evaluation of screening tools, including sustained nighttime snoring.
- Discussion of polysomnography as the gold standard and nightime oximetry as a viable alternative.
- Consideration of sleep obstructive apnea syndrome (SOAS) treatment, primarily adenotonsillectomy.
Main Results:
- Persistent nighttime snoring is a reliable indicator for screening pediatric SRBD.
- Polysomnography remains the gold standard for diagnosis, while nightime oximetry shows high positive predictive value.
- Sleep obstructive apnea syndrome (SOAS) is the most common SRBD in childhood, often managed surgically.
Conclusions:
- Early intervention for pediatric SRBD is essential to mitigate negative impacts on neurocognitive development.
- Adenotonsillectomy is a common treatment for pediatric SOAS.
- Further research is needed to define the long-term outcomes of pediatric SOAS and the utility of outpatient polygraphy.
Abstract:
Sleep related breathing disorders (SDB) in children has a major negative impact on their neurocognitive development and should be identified and treated early as to decrease morbidity. Children do not usually present daytime fatigue and sleepiness like adults, but rather show abnormal behavior patterns and learning disabilities. The presence of sustained nightime snoring is a good screening toll for SDB. Polysomnography is the gold standard for diagnosis even though nightime oxymetry, with its high positive predictive value, can also be used. The most frequent SDB in childhood is sleep obstructive apnea syndrome (SOAS), which generally requires surgical treatment with adenotonsillectomy. Long term evolution of pediatric SOAS still has to be defined, as the role of other diagnostic tools such as outpatient polygraphy.
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