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Molecular and Ionic Solids

Molecular and Ionic Solids

Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...

Common Ion Effect

Common Ion Effect

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:

Solubility of Ionic Compounds

Solubility of Ionic Compounds

Solubility is the measure of the maximum amount of solute that can be dissolved in a given quantity of solvent at a given temperature and pressure. Solubility is usually measured in molarity (M) or moles per liter (mol/L). A compound is termed soluble if it dissolves in water.

Ion Exchange

Ion Exchange

Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or basic...

Ionic Association

Ionic Association

The ionic association is the association of oppositely charged ions in an electrolyte solution to form ion pairs. Bjerrum defined ion pairs as two oppositely charged ions whose electrostatic attraction exceeds the thermal energy of the system, typically expressed as 2kT. Electrostatic attraction depends on ionic charge, separation distance, and the dielectric constant of the medium. Thermal energy, represented by kT, reflects the tendency of ions to move independently due to molecular motion.

Factors Affecting Solubility

Factors Affecting Solubility

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:

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Updated: Jul 6, 2026

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

Methimazole-based ionic liquids.

Amal I Siriwardana¹, Ian R Crossley, Angel A J Torriero

¹School of Chemistry, Monash University, Clayton, VIC, Australia. amal.siriwardana@sci.monash.edu.au

The Journal of Organic Chemistry

|April 12, 2008

Summary

This summary is machine-generated.

Researchers synthesized novel methimazole-based room-temperature ionic liquids. These compounds were created through alkylation and anion metathesis reactions, yielding high product purity and demonstrating the thione tautomer

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Area of Science:

Organic Chemistry
Materials Science
Ionic Liquids

Background:

Methimazole is a key pharmaceutical compound.
Ionic liquids offer unique solvent properties.
Exploring novel ionic liquid structures is crucial for advanced applications.

Purpose of the Study:

To synthesize novel methimazole-based room-temperature ionic liquids (RTILs).
To investigate the alkylation reaction pathway of methimazole.
To characterize the properties of the synthesized RTILs.

Main Methods:

Alkylation of 2-mercapto-1-methylimidazole with iodoethane and chlorobutane.
Anion metathesis of S-alkylmethimazole halides with metal salts.
Purification and characterization of the resulting ionic liquids.

Main Results:

Successfully synthesized three methimazole-based RTILs (3a, 3b, 3c) in high yields (82-87%).
The S-alkylation products (2a, 2b) indicate methimazole reacts via its thione tautomer.
The synthesized ionic liquids exhibit potential for various chemical applications.

Conclusions:

The study demonstrates a facile synthetic route to novel methimazole-based RTILs.
Reaction mechanism insights confirm the thione tautomer's role in methimazole alkylation.
These RTILs represent a promising class of compounds for further research and development.